An Adsorptive and Antioxidant Vaginal Gel Clears High-Risk HPV- and p16/Ki-67-Associated Abnormal Cytological Cervical Findings: A post-hoc Subgroup Analysis of a Prospective Randomized Controlled Trial on CIN2 and p16 Positive CIN1

An Adsorptive and Antioxidant Vaginal Gel Clears High-Risk HPV- and p16/Ki-67-Associated Abnormal Cytological Cervical Findings: A post-hoc Subgroup Analysis of a Prospective Randomized Controlled Trial on CIN2 and p16 Positive CIN1

Objective: To analyze the course of p16/Ki-67-positive abnormal cytological cervical findings and high risk (hr)-HPV- and p16/Ki-67-clearances in women treated with a vaginal gel.Methods: 172 women with a histological diagnosis of CIN2 or p16-positive CIN1 lesions were selected based on a positive c...

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Bibliographic Details
Main Authors: Attila Louis Major, Ales Skřivánek, Etienne Marc Grandjean, Vladimír Dvořák, Tomáš Malík, Marek Pluta, Ivanna Mayboroda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Medicine
Subjects:
cervical intraepithelial neoplasia
abnormal cervical smear findings
high risk HPV
p16/Ki-67 biomarker
adsorptive and antioxidative vaginal gel
silicon dioxide
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.645559/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.645559/full

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