Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion

Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion

Summary:. Aggressive angiomyxoma is a very rare benign tumor for male population with fewer than 50 cases reported since the description of this tumor. Most documented cases of aggressive angiomyxomas were found in genital, perineal, and pelvic regions in women of child bearing age. We report a case...

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Main Authors: Frank Hsieh, MA, MBBChir, FRACS, Kai-Ti Chuang, MD, You-Ting Wu, MD, Chih-Hung Lin, MD
Format: Article
Language:English
Published: Wolters Kluwer 2018-08-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001879
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spelling doaj-f7747a283a8c422188f0d38a6d3d99062020-11-25T00:12:01ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742018-08-0168e187910.1097/GOX.0000000000001879201808000-00035Aggressive Angiomyxoma—Report of a Rare Male Buttock LesionFrank Hsieh, MA, MBBChir, FRACS0Kai-Ti Chuang, MD1You-Ting Wu, MD2Chih-Hung Lin, MD3From the * Department of Plastic & Reconstructive Surgery, Chiayi Chang Gung Memorial Hospital, Chang Gung University, TaiwanFrom the * Department of Plastic & Reconstructive Surgery, Chiayi Chang Gung Memorial Hospital, Chang Gung University, Taiwan† Department of Laboratory Medicine, Chiayi Chang Gung Memorial Hospital, Chang Gung University, Taiwan.From the * Department of Plastic & Reconstructive Surgery, Chiayi Chang Gung Memorial Hospital, Chang Gung University, TaiwanSummary:. Aggressive angiomyxoma is a very rare benign tumor for male population with fewer than 50 cases reported since the description of this tumor. Most documented cases of aggressive angiomyxomas were found in genital, perineal, and pelvic regions in women of child bearing age. We report a case of a massive (> 20 cm) aggressive angiomyxomas in a man who presented with perineal swellings. Macroscopically the mass was highly vascular and lobulated with high similarity to plexiform neurofibroma. Microscopic examination revealed a hypocellular tumor comprising bland oval and spindle-shaped cells along with vessels of varying calibre. The accompanying stroma was myxocollagenous. Immunohistochemical staining showed CD34 and focal estrogen receptors positivity and negative staining for S100, actin, desmin, and progesterone receptors. The histologic and immunohistochemical features favored the diagnosis of aggressive angiomyxoma. Despite the rarity of such tumor in the male population, aggressive angiomyxoma should be considered in the differential diagnosis when encountering chronic para-perineal lesions.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001879
collection DOAJ
language English
format Article
sources DOAJ
author Frank Hsieh, MA, MBBChir, FRACS
Kai-Ti Chuang, MD
You-Ting Wu, MD
Chih-Hung Lin, MD
spellingShingle Frank Hsieh, MA, MBBChir, FRACS
Kai-Ti Chuang, MD
You-Ting Wu, MD
Chih-Hung Lin, MD
Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion
Plastic and Reconstructive Surgery, Global Open
author_facet Frank Hsieh, MA, MBBChir, FRACS
Kai-Ti Chuang, MD
You-Ting Wu, MD
Chih-Hung Lin, MD
author_sort Frank Hsieh, MA, MBBChir, FRACS
title Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion
title_short Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion
title_full Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion
title_fullStr Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion
title_full_unstemmed Aggressive Angiomyxoma—Report of a Rare Male Buttock Lesion
title_sort aggressive angiomyxoma—report of a rare male buttock lesion
publisher Wolters Kluwer
series Plastic and Reconstructive Surgery, Global Open
issn 2169-7574
publishDate 2018-08-01
description Summary:. Aggressive angiomyxoma is a very rare benign tumor for male population with fewer than 50 cases reported since the description of this tumor. Most documented cases of aggressive angiomyxomas were found in genital, perineal, and pelvic regions in women of child bearing age. We report a case of a massive (> 20 cm) aggressive angiomyxomas in a man who presented with perineal swellings. Macroscopically the mass was highly vascular and lobulated with high similarity to plexiform neurofibroma. Microscopic examination revealed a hypocellular tumor comprising bland oval and spindle-shaped cells along with vessels of varying calibre. The accompanying stroma was myxocollagenous. Immunohistochemical staining showed CD34 and focal estrogen receptors positivity and negative staining for S100, actin, desmin, and progesterone receptors. The histologic and immunohistochemical features favored the diagnosis of aggressive angiomyxoma. Despite the rarity of such tumor in the male population, aggressive angiomyxoma should be considered in the differential diagnosis when encountering chronic para-perineal lesions.
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001879
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