Structural and Functional Peculiarities of Cytoplasmic Tropomyosin Isoforms, the Products of <i>TPM1</i> and <i>TPM4</i> Genes

Structural and Functional Peculiarities of Cytoplasmic Tropomyosin Isoforms, the Products of <i>TPM1</i> and <i>TPM4</i> Genes

Tropomyosin (Tpm) is one of the major protein partners of actin. Tpm molecules are <i>α</i>-helical coiled-coil protein dimers forming a continuous head-to-tail polymer along the actin filament. Human cells produce a large number of Tpm isoforms that are thought to play a significant rol...

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Bibliographic Details
Main Authors: Marina Marchenko, Victoria Nefedova, Natalia Artemova, Sergey Kleymenov, Dmitrii Levitsky, Alexander Matyushenko
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
tropomyosin
cytoplasmic isoforms
actin filaments
circular dichroism
differential scanning calorimetry
Online Access:https://www.mdpi.com/1422-0067/22/10/5141

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