Participation of PKG and PKA-related pathways in the IFN-γ induced modulation of the BKCa channel activity in human cardiac fibroblasts

This study was devoted to elucidating the interferon (IFN)-γ-induced signaling pathway and the interaction between protein kinase G (PKG) and protein kinase A (PKA) through large-conductance Ca(2+)-activated K(+) channels in human cardiac fibroblasts. The IK currents were recorded using a whole-cell...

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Bibliographic Details
Main Authors: M.V. Mitrokhin, V. Kalsin, O. Kamkina, I. Babkina, A. Zotov, V.A. Troitskiy, M.I. Mladenov, G.A. Kamkin
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319357020