Pre-Leukemic States: United by Difference

Pre-leukemia is a catch-all term for any haematological condition which predisposes the individual towards developing leukemia. The development of any cancer begins long before any clinically detectable sign is apparent. It requires a series of driver acquisition events, each providing a growth or s...

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Bibliographic Details
Main Author: Christopher I. Slape
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
n/a
Online Access:https://www.mdpi.com/2072-6694/13/6/1382
Description
Summary:Pre-leukemia is a catch-all term for any haematological condition which predisposes the individual towards developing leukemia. The development of any cancer begins long before any clinically detectable sign is apparent. It requires a series of driver acquisition events, each providing a growth or survival advantage to a cell such that it will expand. Each clonally selected event is followed by another, until eventually, the clone reaches the definition of what we call cancer. It is sometimes difficult to discriminate cancer from non-cancer, and experts will disagree in some cases on whether a particular sample is cancerous or pre-malignant. What is [...]
ISSN:2072-6694