Abnormal cisatracurium pharmacodynamics and pharmacokinetics among patients with severe aortic regurgitation during anesthetic induction

Abnormal cisatracurium pharmacodynamics and pharmacokinetics among patients with severe aortic regurgitation during anesthetic induction

Abstract Background This study was designed to examine whether severe aortic regurgitation will affect the pharmacodynamics (PD) and pharmacokinetics (PK) of cisatracurium during anesthetic induction. Methods A total of 32 patients were divided into two groups: the AR group (n = 16) and the control...

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Bibliographic Details
Main Authors: Xiaocong Huang, Lei Chen, Yujing Cai, Jinfeng Wei, Lina Lin, Jie Sun, Xuemei Peng, Sheng Wang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Anesthesiology
Subjects:
Cisatracurium
Severe aortic regurgitation
Neuromuscular blockade
Intercompartment transfer rate
Online Access:https://doi.org/10.1186/s12871-020-0935-z

Internet

https://doi.org/10.1186/s12871-020-0935-z

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