Vaccination with M2e-based multiple antigenic peptides: characterization of the B cell response and protection efficacy in inbred and outbred mice.

Vaccination with M2e-based multiple antigenic peptides: characterization of the B cell response and protection efficacy in inbred and outbred mice.

The extracellular domain of the influenza A virus protein matrix protein 2 (M2e) is remarkably conserved between various human isolates and thus is a viable target antigen for a universal influenza vaccine. With the goal of inducing protection in multiple mouse haplotypes, M2e-based multiple antigen...

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Bibliographic Details
Main Authors: Amaya I Wolf, Krystyna Mozdzanowska, Katie L Williams, David Singer, Monique Richter, Ralf Hoffmann, Andrew J Caton, Laszlo Otvos, Jan Erikson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3236751?pdf=render

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http://europepmc.org/articles/PMC3236751?pdf=render

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