NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling

NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling

Stem cells derived from elderly donors or harvested by repeated subculture exhibit a marked decrease in proliferative capacity and multipotency, which not only compromises their therapeutic potential but also raises safety concerns for regenerative medicine. NANOG—a well-known core transcription fac...

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Bibliographic Details
Main Authors:	Feilin Liu, Jiahong Shi, Yingyao Zhang, Aobo Lian, Xing Han, Kuiyang Zuo, Mingsheng Liu, Tong Zheng, Fei Zou, Xiaomei Liu, Minghua Jin, Ying Mu, Gang Li, Guanfang Su, Jinyu Liu
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2019/4286213

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