PHOSPHONATED ISOXAZOLIDINYL NUCLEOSIDES, A NEW CLASS OF MODIFIED NUCLEOSIDES

This review offers an overview of the synthesis of phosphonated isoxazolidinyl nucleosides, a new class of interesting and potentially antiviral/antitumor agents. The synthetic methodology relies on a 1,3-dipolar cycloaddition reaction as a key step. The cycloaddition process involves substituted...

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Bibliographic Details
Main Author: Salvatore Giofrè
Format: Article
Language:English
Published: Associazione Italiana Giovani Medici 2014-04-01
Series:Euromediterranean Biomedical Journal
Online Access:http://www.embj.org/images/ISSUE_2014/giofre_7.pdf