Early hypothalamic FTO overexpression in response to maternal obesity--potential contribution to postweaning hyperphagia.

Intrauterine and postnatal overnutrition program hyperphagia, adiposity and glucose intolerance in offspring. Single-nucleotide polymorphisms (SNPs) of the fat mass and obesity associated (FTO) gene have been linked to increased risk of obesity. FTO is highly expressed in hypothalamic regions critic...

Full description

Bibliographic Details
Main Authors: Vanni Caruso, Hui Chen, Margaret J Morris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182187?pdf=render