Novel anti-inflammatory compound from Prosopis africana

An active natural flavanone compound: 3,7,3,4-tetrahydroxyflavanone, 3- protocatechuate obtained from the stem barks of Prosopis Africana, tested against inflammation and showed a significant anti-inflammatory activity inhibiting COX-2 and iNOS at concentration of 20mM. The structure was establis...

Full description

Bibliographic Details
Main Authors: JAMAL MEZOGI, HAFSAT SHITTU, RUANGELIE EDRADA-EBEL, VERONIQUE SEIDEL, ALEXANDER GRAY, YOUSEF A TAHER, GHAZALLA BENHUSEIN
Format: Article
Language:English
Published: Phytochemistry & Organic Synthesis Laboratory 2017-11-01
Series:PhytoChem & BioSub Journal
Online Access:https://drive.google.com/file/d/10DUmOEimcNEVjMkQL2MVo6LX70lhFObw/view?usp=sharing
id doaj-f70fb33228b7467aaa6d07d0a0f1fc49
record_format Article
spelling doaj-f70fb33228b7467aaa6d07d0a0f1fc492020-11-25T00:37:03ZengPhytochemistry & Organic Synthesis LaboratoryPhytoChem & BioSub Journal2170-17682170-17682017-11-01113Novel anti-inflammatory compound from Prosopis africana JAMAL MEZOGI, 0HAFSAT SHITTURUANGELIE EDRADA-EBELVERONIQUE SEIDELALEXANDER GRAYYOUSEF A TAHERGHAZALLA BENHUSEIN1Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UKFaculty of pharmacy, University of Tripoli, LibyaAn active natural flavanone compound: 3,7,3,4-tetrahydroxyflavanone, 3- protocatechuate obtained from the stem barks of Prosopis Africana, tested against inflammation and showed a significant anti-inflammatory activity inhibiting COX-2 and iNOS at concentration of 20mM. The structure was established on the basis of their UV, NMR (1D and 2D) spectra, mass spectrometry and polarimeter. https://drive.google.com/file/d/10DUmOEimcNEVjMkQL2MVo6LX70lhFObw/view?usp=sharing
collection DOAJ
language English
format Article
sources DOAJ
author JAMAL MEZOGI,
HAFSAT SHITTU
RUANGELIE EDRADA-EBEL
VERONIQUE SEIDEL
ALEXANDER GRAY
YOUSEF A TAHER
GHAZALLA BENHUSEIN
spellingShingle JAMAL MEZOGI,
HAFSAT SHITTU
RUANGELIE EDRADA-EBEL
VERONIQUE SEIDEL
ALEXANDER GRAY
YOUSEF A TAHER
GHAZALLA BENHUSEIN
Novel anti-inflammatory compound from Prosopis africana
PhytoChem & BioSub Journal
author_facet JAMAL MEZOGI,
HAFSAT SHITTU
RUANGELIE EDRADA-EBEL
VERONIQUE SEIDEL
ALEXANDER GRAY
YOUSEF A TAHER
GHAZALLA BENHUSEIN
author_sort JAMAL MEZOGI,
title Novel anti-inflammatory compound from Prosopis africana
title_short Novel anti-inflammatory compound from Prosopis africana
title_full Novel anti-inflammatory compound from Prosopis africana
title_fullStr Novel anti-inflammatory compound from Prosopis africana
title_full_unstemmed Novel anti-inflammatory compound from Prosopis africana
title_sort novel anti-inflammatory compound from prosopis africana
publisher Phytochemistry & Organic Synthesis Laboratory
series PhytoChem & BioSub Journal
issn 2170-1768
2170-1768
publishDate 2017-11-01
description An active natural flavanone compound: 3,7,3,4-tetrahydroxyflavanone, 3- protocatechuate obtained from the stem barks of Prosopis Africana, tested against inflammation and showed a significant anti-inflammatory activity inhibiting COX-2 and iNOS at concentration of 20mM. The structure was established on the basis of their UV, NMR (1D and 2D) spectra, mass spectrometry and polarimeter.
url https://drive.google.com/file/d/10DUmOEimcNEVjMkQL2MVo6LX70lhFObw/view?usp=sharing
work_keys_str_mv AT jamalmezogi novelantiinflammatorycompoundfromprosopisafricana
AT hafsatshittu novelantiinflammatorycompoundfromprosopisafricana
AT ruangelieedradaebel novelantiinflammatorycompoundfromprosopisafricana
AT veroniqueseidel novelantiinflammatorycompoundfromprosopisafricana
AT alexandergray novelantiinflammatorycompoundfromprosopisafricana
AT yousefataher novelantiinflammatorycompoundfromprosopisafricana
AT ghazallabenhusein novelantiinflammatorycompoundfromprosopisafricana
_version_ 1725302845885906944