Novel anti-inflammatory compound from Prosopis africana

Novel anti-inflammatory compound from Prosopis africana

An active natural flavanone compound: 3,7,3,4-tetrahydroxyflavanone, 3- protocatechuate obtained from the stem barks of Prosopis Africana, tested against inflammation and showed a significant anti-inflammatory activity inhibiting COX-2 and iNOS at concentration of 20mM. The structure was establis...

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Bibliographic Details
Main Authors: JAMAL MEZOGI, HAFSAT SHITTU, RUANGELIE EDRADA-EBEL, VERONIQUE SEIDEL, ALEXANDER GRAY, YOUSEF A TAHER, GHAZALLA BENHUSEIN
Format: Article
Language:English
Published: Phytochemistry & Organic Synthesis Laboratory 2017-11-01
Series:PhytoChem & BioSub Journal
Online Access:https://drive.google.com/file/d/10DUmOEimcNEVjMkQL2MVo6LX70lhFObw/view?usp=sharing
Description
Summary:An active natural flavanone compound: 3,7,3,4-tetrahydroxyflavanone, 3- protocatechuate obtained from the stem barks of Prosopis Africana, tested against inflammation and showed a significant anti-inflammatory activity inhibiting COX-2 and iNOS at concentration of 20mM. The structure was established on the basis of their UV, NMR (1D and 2D) spectra, mass spectrometry and polarimeter.
ISSN:2170-1768
2170-1768

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