Peripheral Nerve Regeneration through Hydrogel-Enriched Chitosan Conduits Containing Engineered Schwann Cells for Drug Delivery

Peripheral Nerve Regeneration through Hydrogel-Enriched Chitosan Conduits Containing Engineered Schwann Cells for Drug Delivery

Critical length nerve defects in the rat sciatic nerve model were reconstructed with chitosan nerve guides filled with Schwann cells (SCs) containing hydrogel. The transplanted SCs were naive or had been genetically modified to overexpress neurotrophic factors, thus providing a cellular neurotrophic...

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Bibliographic Details
Main Authors: Cora Meyer, Sandra Wrobel, Stefania Raimondo, Shimon Rochkind, Claudia Heimann, Abraham Shahar, Ofra Ziv-Polat, Stefano Geuna, Claudia Grothe, Kirsten Haastert-Talini
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X688010

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