The effects of Nigella sativa hydro-alcoholic extract and thymoquinone on lipopolysaccharide - induced depression like behavior in rats

The effects of Nigella sativa hydro-alcoholic extract and thymoquinone on lipopolysaccharide - induced depression like behavior in rats

Background: Neuroimmune factors have been proposed as contributors to the pathogenesis of depression. Beside other therapeutic effects including neuroprotective, antioxidant, anticonvulsant and analgesic effects, Nigella sativa and its main ingredient, thymoquinone (TQ), have been shown to have anti...

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Bibliographic Details
Main Authors: Mahmoud Hosseini, Samaneh Zakeri, Sadieh Khoshdast, Fatemeh T Yousefian, Monireh Rastegar, Farzaneh Vafaee, Shamsi Kahdouee, Fatemeh Ghorbani, Hassan Rakhshandeh, S Abolfazl Kazemi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Depression
forced swimming test
lipopolysaccharide
Nigella sativa
open-field
thymoquinone
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=3;spage=219;epage=225;aulast=Hosseini

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