Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity.

Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity.

RecQ helicases are essential for the maintenance of chromosome stability. In addition to DNA unwinding, some RecQ enzymes have an intrinsic DNA strand annealing activity. The function of this dual enzymatic activity and the mechanism that regulates it is, however, unknown. Here, we describe two quat...

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Bibliographic Details
Main Authors: Laura Muzzolini, Fabienne Beuron, Ardan Patwardhan, Venkateswarlu Popuri, Sheng Cui, Benedetta Niccolini, Mathieu Rappas, Paul S Freemont, Alessandro Vindigni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0050020

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https://doi.org/10.1371/journal.pbio.0050020

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