Effect of Ammonium Chloride in addition to standard of care in outpatients and hospitalized COVID-19 patients: A randomized clinical trial
Objective: The COVID-19 pandemic has called an urgent need for drug repurposing to improve the outcome of the disease. Quaternary ammonium compounds have been demonstrated to have antiviral effects and may be of use against SARS-CoV-2 infections. Design: In this double-blind, single-center study, we...
Main Authors: | Zeinab Siami, Sepehr Aghajanian, Somayeh Mansouri, Zakiye Mokhames, Reza Pakzad, Kourosh Kabir, Mehdi Norouzi, Alireza Soleimani, Mojtaba Hedayat Yaghoobi, Shahrzad Shadabi, Ramin Tajbakhsh, Ali Kargar Kheirabad, Sayed-Hamidreza Mozhgani |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-07-01
|
Series: | International Journal of Infectious Diseases |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971221003544 |
Similar Items
-
Rational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19
by: Markus Blaess, et al.
Published: (2020-11-01) -
Lysosomotropic Features and Autophagy Modulators among Medical Drugs: Evaluation of Their Role in Pathologies
by: Tatiana A. Korolenko, et al.
Published: (2020-10-01) -
Treatment of COVID19 with antimalarial medicines: clinical pharmacology analysis
by: Kolbin A.S.
Published: (2020-10-01) -
Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells
by: Aida Paivandy, et al.
Published: (2017-11-01) -
Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics
by: Allemailem KS, et al.
Published: (2021-07-01)