Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19

The main basis for hydroxychloroquine (HCQ) treatment in COVID-19 is the compound’s ability to inhibit viral replication in vitro. HCQ also suppresses immunity, mainly by interference in TLR signalling, but reliable clinical data on the extent and nature of HCQ-induced immunosuppression are lacking....

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Bibliographic Details
Main Authors: Aliede E. in ‘t Veld, Manon A. A. Jansen, Luuk C. A. Ciere, Matthijs Moerland
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2021/6659410