Potential of minimally invasive procedures in the treatment of uterine fibroids: a focus on magnetic resonance-guided focused ultrasound therapy

• Main Authors: Fischer K, McDannold NJ, Tempany CM, Jolesz FA, Fennessy FM
• Format: Article
• Language: English
• Published: Dove Medical Press 2015-11-01
• Series: International Journal of Women's Health
• Online Access: https://www.dovepress.com/potential-of-minimally-invasive-procedures-in-the-treatment-of-uterine-peer-reviewed-article-IJWH

Krisztina Fischer,1–3 Nathan J McDannold,1 Clare M Tempany,1 Ferenc A Jolesz,1,† Fiona M Fennessy1,4 1Department of Radiology, 2Renal Division, 3Biomedical Engineering Division, Brigham and Women’s Hospital, 4Department of Radiology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA †Ferenc A Jolesz passed away on December 31, 2014 Abstract: Minimally invasive treatment options are an important part of the uterine fibroid-treatment arsenal, especially among younger patients and in those who plan future pregnancies. This article provides an overview of the currently available minimally invasive therapy options, with a special emphasis on a completely noninvasive option: magnetic resonance-guided focused ultrasound (MRgFUS). In this review, we describe the background of MRgFUS, the patient-selection criteria for MRgFUS, and how the procedure is performed. We summarize the published clinical trial results, and review the literature on pregnancy post-MRgFUS and on the cost-effectiveness of MRgFUS. Keywords: uterine fibroids, MRgFUS, focused ultrasound, minimally invasive treatment