The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome.

Chromatin structure plays an important role in modulating the accessibility of genomic DNA to regulatory proteins in eukaryotic cells. We performed an integrative analysis on dozens of recent datasets generated by deep-sequencing and high-density tiling arrays, and we discovered an array of well-pos...

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Bibliographic Details
Main Authors: Yutao Fu, Manisha Sinha, Craig L Peterson, Zhiping Weng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2453330?pdf=render