Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer

Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer

CXCR4 is a chemokine receptor crucial in tumor progression, although the angiogenic role of CXCR4 in oral squamous cell carcinoma (OSCC) has not been investigated. Here we show that CXCR4 is crucial for tumor angiogenesis, thereby supporting tumor survival in OSCC. Immunohistochemistry on human clin...

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Bibliographic Details
Main Authors: Saori Yoshida, Hotaka Kawai, Takanori Eguchi, Shintaro Sukegawa, May Wathone Oo, Chang Anqi, Kiyofumi Takabatake, Keisuke Nakano, Kuniaki Okamoto, Hitoshi Nagatsuka
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
tumor blood vessel
tumor angiogenic inhibition triggered necrosis (TAITN)
CXCR4 antagonist
oral squamous cell carcinoma
hypoxia
Online Access:https://www.mdpi.com/2073-4409/8/7/761

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