Relationship between insertion/deletion (indel) frequency of proteins and essentiality

<p>Abstract</p> <p>Background</p> <p>In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human proteins of high sequence similarity. Such indels may provide sufficien...

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Bibliographic Details
Main Authors: Hormozdiari Fereydoun, Hsing Michael, Chan Simon K, Cherkasov Artem
Format: Article
Language:English
Published: BMC 2007-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/227