Conversion of the Sensor Kinase DcuS to the Fumarate Sensitive State by Interaction of the Bifunctional Transporter DctA at the TM2/PAS<sub>C</sub>-Linker Region

Conversion of the Sensor Kinase DcuS to the Fumarate Sensitive State by Interaction of the Bifunctional Transporter DctA at the TM2/PAS<sub>C</sub>-Linker Region

The membrane-bound C<sub>4</sub>-dicarboxylate (C4DC) sensor kinase DcuS of <i>Escherichia coli</i> typically forms a protein complex with the C4DC transporter DctA. The DctA × DcuS complex is able to respond to C4DCs, whereas DcuS without DctA is in the permanent ON state. I...

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Bibliographic Details
Main Authors: Marius Stopp, Christopher Schubert, Gottfried Unden
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Microorganisms
Subjects:
sensor kinase DcuS
bifunctional transporter DctA
sensor complex
structural co-regulator
Online Access:https://www.mdpi.com/2076-2607/9/7/1397

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