Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids

An environmentally-friendly and easy synthesis of a series of novel functionalized imidazolium-based ionic liquids (ILs) is described under both the conventional procedure and microwave irradiation. The structures of newly synthesized room-temperature ionic liquids (RTILs) were established by differ...

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Main Authors:	Ahmed H. Albalawi, Wael S. El-Sayed, Ateyatallah Aljuhani, Saud M. Almutairi, Nadjet Rezki, Mohamed R. Aouad, Mouslim Messali
Format:	Article
Language:	English
Published:	MDPI AG 2018-07-01
Series:	Molecules
Subjects:	ionic liquids imidazolium green synthesis microwave irradiation toxicity antibacterial activity
Online Access:	http://www.mdpi.com/1420-3049/23/7/1727

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spelling	doaj-f6acb3e7b1db4b6b8100a55bffa210b92020-11-24T23:05:54ZengMDPI AGMolecules1420-30492018-07-01237172710.3390/molecules23071727molecules23071727Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic LiquidsAhmed H. Albalawi0Wael S. El-Sayed1Ateyatallah Aljuhani2Saud M. Almutairi3Nadjet Rezki4Mohamed R. Aouad5Mouslim Messali6Department of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaDepartment of Biology Department, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaDepartment of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaKing Abdulaziz City for Science and Technology, Riyadh 11442, P.O. Box 6086, Saudi ArabiaDepartment of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaDepartment of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaDepartment of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi ArabiaAn environmentally-friendly and easy synthesis of a series of novel functionalized imidazolium-based ionic liquids (ILs) is described under both the conventional procedure and microwave irradiation. The structures of newly synthesized room-temperature ionic liquids (RTILs) were established by different spectral analyses. All ILs (1–14) were screened for their in vitro antimicrobial activity against a panel of clinically isolated bacteria. The results of the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) showed that some of the tested ILs are very promising anti-bacterial agents especially those containing an alkyl chain with a phenyl group (most notably 1, 2, 12, and 13).http://www.mdpi.com/1420-3049/23/7/1727ionic liquidsimidazoliumgreen synthesismicrowave irradiationtoxicityantibacterial activity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ahmed H. Albalawi Wael S. El-Sayed Ateyatallah Aljuhani Saud M. Almutairi Nadjet Rezki Mohamed R. Aouad Mouslim Messali
spellingShingle	Ahmed H. Albalawi Wael S. El-Sayed Ateyatallah Aljuhani Saud M. Almutairi Nadjet Rezki Mohamed R. Aouad Mouslim Messali Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids Molecules ionic liquids imidazolium green synthesis microwave irradiation toxicity antibacterial activity
author_facet	Ahmed H. Albalawi Wael S. El-Sayed Ateyatallah Aljuhani Saud M. Almutairi Nadjet Rezki Mohamed R. Aouad Mouslim Messali
author_sort	Ahmed H. Albalawi
title	Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids
title_short	Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids
title_full	Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids
title_fullStr	Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids
title_full_unstemmed	Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids
title_sort	microwave-assisted synthesis of some potential bioactive imidazolium-based room-temperature ionic liquids
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2018-07-01
description	An environmentally-friendly and easy synthesis of a series of novel functionalized imidazolium-based ionic liquids (ILs) is described under both the conventional procedure and microwave irradiation. The structures of newly synthesized room-temperature ionic liquids (RTILs) were established by different spectral analyses. All ILs (1–14) were screened for their in vitro antimicrobial activity against a panel of clinically isolated bacteria. The results of the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) showed that some of the tested ILs are very promising anti-bacterial agents especially those containing an alkyl chain with a phenyl group (most notably 1, 2, 12, and 13).
topic	ionic liquids imidazolium green synthesis microwave irradiation toxicity antibacterial activity
url	http://www.mdpi.com/1420-3049/23/7/1727
work_keys_str_mv	AT ahmedhalbalawi microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids AT waelselsayed microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids AT ateyatallahaljuhani microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids AT saudmalmutairi microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids AT nadjetrezki microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids AT mohamedraouad microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids AT mouslimmessali microwaveassistedsynthesisofsomepotentialbioactiveimidazoliumbasedroomtemperatureionicliquids
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Microwave-Assisted Synthesis of Some Potential Bioactive Imidazolium-Based Room-Temperature Ionic Liquids

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