Quantitation of 4,4′-methylene diphenyl diisocyanate human serum albumin adducts

Quantitation of 4,4′-methylene diphenyl diisocyanate human serum albumin adducts

4,4′-Methylene diphenyl diisocyanate (herein 4,4′-MDI) is used in the production of polyurethane foams, elastomers, coatings, adhesives and the like for a wide range of commercial products. Occupational exposure to MDI levels above current airborne exposure limits can elicit immune mediated hypersen...

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Bibliographic Details
Main Authors: Leah G. Luna, Brett J. Green, Fagen Zhang, Scott M. Arnold, Paul D. Siegel, Michael J. Bartels
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
MDI
Adduct
Mass spectrometry
Diisocyanates
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000900

Internet

http://www.sciencedirect.com/science/article/pii/S2214750014000900

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