Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli

Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli

Cellular proteome allocation in response to environmental or internal perturbations governs their eventual phenotypic outcome. This entails striking an effective balance between amino acid biosynthesis by metabolic proteins and its consumption by ribosomes.

Bibliographic Details
Main Authors: Mahesh S. Iyer, Ankita Pal, Sumana Srinivasan, Pramod R. Somvanshi, K. V. Venkatesh
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mSystems
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00001-21
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spelling doaj-f6a71fe7904a4a87a3b5f359b1868d282021-09-21T20:42:22ZengAmerican Society for MicrobiologymSystems2379-50772021-04-016210.1128/mSystems.00001-21Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coliMahesh S. Iyer0Ankita Pal1Sumana Srinivasan2Pramod R. Somvanshi3K. V. Venkatesh4https://orcid.org/0000-0001-7397-5472Department of Chemical Engineering, Indian Institute of Technology Bombay, Mumbai, IndiaDepartment of Chemical Engineering, Indian Institute of Technology Bombay, Mumbai, IndiaDepartment of Chemical Engineering, Indian Institute of Technology Bombay, Mumbai, IndiaDepartment of Chemical Engineering, Indian Institute of Technology Bombay, Mumbai, IndiaDepartment of Chemical Engineering, Indian Institute of Technology Bombay, Mumbai, India Cellular proteome allocation in response to environmental or internal perturbations governs their eventual phenotypic outcome. This entails striking an effective balance between amino acid biosynthesis by metabolic proteins and its consumption by ribosomes.https://journals.asm.org/doi/10.1128/mSystems.00001-21
collection DOAJ
language English
format Article
sources DOAJ
author Mahesh S. Iyer
Ankita Pal
Sumana Srinivasan
Pramod R. Somvanshi
K. V. Venkatesh
spellingShingle Mahesh S. Iyer
Ankita Pal
Sumana Srinivasan
Pramod R. Somvanshi
K. V. Venkatesh
Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
mSystems
author_facet Mahesh S. Iyer
Ankita Pal
Sumana Srinivasan
Pramod R. Somvanshi
K. V. Venkatesh
author_sort Mahesh S. Iyer
title Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
title_short Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
title_full Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
title_fullStr Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
title_full_unstemmed Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli
title_sort global transcriptional regulators fine-tune the translational and metabolic efficiency for optimal growth of escherichia coli
publisher American Society for Microbiology
series mSystems
issn 2379-5077
publishDate 2021-04-01
description Cellular proteome allocation in response to environmental or internal perturbations governs their eventual phenotypic outcome. This entails striking an effective balance between amino acid biosynthesis by metabolic proteins and its consumption by ribosomes.
url https://journals.asm.org/doi/10.1128/mSystems.00001-21
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AT sumanasrinivasan globaltranscriptionalregulatorsfinetunethetranslationalandmetabolicefficiencyforoptimalgrowthofescherichiacoli
AT pramodrsomvanshi globaltranscriptionalregulatorsfinetunethetranslationalandmetabolicefficiencyforoptimalgrowthofescherichiacoli
AT kvvenkatesh globaltranscriptionalregulatorsfinetunethetranslationalandmetabolicefficiencyforoptimalgrowthofescherichiacoli
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