Predominant role of plasmacytoid dendritic cells in stimulating systemic autoimmunity

Predominant role of plasmacytoid dendritic cells in stimulating systemic autoimmunity

Plasmacytoid dendritic cells (pDCs), which are prominent type I interferon (IFN-I)-producing immune cells, have been extensively implicated in systemic lupus erythematosus (SLE). However, whether they participate critically in lupus pathogenesis remains unknown. Recent studies using various genetic...

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Bibliographic Details
Main Authors:	Xinfang eHuang, Stephanie eDorta-Estremer, Yihong eYao, Nan eShen, Wei eCao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-10-01
Series:	Frontiers in Immunology
Subjects:	Amyloid Autoimmunity Interferon Type I Interferon-alpha Interferons Lupus Erythematosus, Systemic
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00526/full

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