Predominant role of plasmacytoid dendritic cells in stimulating systemic autoimmunity

Predominant role of plasmacytoid dendritic cells in stimulating systemic autoimmunity

Plasmacytoid dendritic cells (pDCs), which are prominent type I interferon (IFN-I)-producing immune cells, have been extensively implicated in systemic lupus erythematosus (SLE). However, whether they participate critically in lupus pathogenesis remains unknown. Recent studies using various genetic...

Full description

Bibliographic Details
Main Authors: Xinfang eHuang, Stephanie eDorta-Estremer, Yihong eYao, Nan eShen, Wei eCao
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Amyloid
Autoimmunity
Interferon Type I
Interferon-alpha
Interferons
Lupus Erythematosus, Systemic
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00526/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00526/full

Similar Items