Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors

Aptamers, in sensing technology, are famous for their role as receptors in versatile applications due to their high specificity and selectivity to a wide range of targets including proteins, small molecules, oligonucleotides, metal ions, viruses, and cells. The outburst of field-effect transistors p...

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Main Authors: Cao-An Vu, Wen-Yih Chen
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/680
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spelling doaj-f69c2c85e651447099ff986b9d50f4512020-11-25T02:06:05ZengMDPI AGMolecules1420-30492020-02-0125368010.3390/molecules25030680molecules25030680Predicting Future Prospects of Aptamers in Field-Effect Transistor BiosensorsCao-An Vu0Wen-Yih Chen1Department of Chemical and Materials Engineering, National Central University, Jhongli 320, TaiwanDepartment of Chemical and Materials Engineering, National Central University, Jhongli 320, TaiwanAptamers, in sensing technology, are famous for their role as receptors in versatile applications due to their high specificity and selectivity to a wide range of targets including proteins, small molecules, oligonucleotides, metal ions, viruses, and cells. The outburst of field-effect transistors provides a label-free detection and ultra-sensitive technique with significantly improved results in terms of detection of substances. However, their combination in this field is challenged by several factors. Recent advances in the discovery of aptamers and studies of Field-Effect Transistor (FET) aptasensors overcome these limitations and potentially expand the dominance of aptamers in the biosensor market.https://www.mdpi.com/1420-3049/25/3/680aptamersmall moleculefet aptasensorfield-effect transistorstructure-switchingbio-amplifier
collection DOAJ
language English
format Article
sources DOAJ
author Cao-An Vu
Wen-Yih Chen
spellingShingle Cao-An Vu
Wen-Yih Chen
Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors
Molecules
aptamer
small molecule
fet aptasensor
field-effect transistor
structure-switching
bio-amplifier
author_facet Cao-An Vu
Wen-Yih Chen
author_sort Cao-An Vu
title Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors
title_short Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors
title_full Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors
title_fullStr Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors
title_full_unstemmed Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors
title_sort predicting future prospects of aptamers in field-effect transistor biosensors
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2020-02-01
description Aptamers, in sensing technology, are famous for their role as receptors in versatile applications due to their high specificity and selectivity to a wide range of targets including proteins, small molecules, oligonucleotides, metal ions, viruses, and cells. The outburst of field-effect transistors provides a label-free detection and ultra-sensitive technique with significantly improved results in terms of detection of substances. However, their combination in this field is challenged by several factors. Recent advances in the discovery of aptamers and studies of Field-Effect Transistor (FET) aptasensors overcome these limitations and potentially expand the dominance of aptamers in the biosensor market.
topic aptamer
small molecule
fet aptasensor
field-effect transistor
structure-switching
bio-amplifier
url https://www.mdpi.com/1420-3049/25/3/680
work_keys_str_mv AT caoanvu predictingfutureprospectsofaptamersinfieldeffecttransistorbiosensors
AT wenyihchen predictingfutureprospectsofaptamersinfieldeffecttransistorbiosensors
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