Hepatitis C: a critical analysis of therapeutic response predictors

Hepatitis C: a critical analysis of therapeutic response predictors

Treatment of chronic hepatitis C is still unspecific. However, there is great expectancy concerning the new pegylated interferons. As there has been much controversy about the best parameters to determine whether treatment is effective, we analyzed several criteria currently used for evaluation, inc...

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Main Authors: Focaccia R., Siciliano R.F., Santos E.D.B., Boccardo E., Conceição O.J.G., Barbosa U.O., Galante V.C.
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Brazilian Journal of Infectious Diseases
Subjects:
ALT normalization
hepatitis C
viral load reduction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200003
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spelling doaj-f69c2683bf3e478080b406d24bd228062020-11-25T03:10:47ZengElsevierBrazilian Journal of Infectious Diseases1413-86701678-43912002-01-01627481Hepatitis C: a critical analysis of therapeutic response predictorsFocaccia R.Siciliano R.F.Santos E.D.B.Boccardo E.Conceição O.J.G.Barbosa U.O.Galante V.C.Treatment of chronic hepatitis C is still unspecific. However, there is great expectancy concerning the new pegylated interferons. As there has been much controversy about the best parameters to determine whether treatment is effective, we analyzed several criteria currently used for evaluation, including serum alanine aminotransferase (ALT) normalization, viral load reduction and improvement of hepatic histology.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200003ALT normalizationhepatitis Cviral load reduction
collection DOAJ
language English
format Article
sources DOAJ
author Focaccia R.
Siciliano R.F.
Santos E.D.B.
Boccardo E.
Conceição O.J.G.
Barbosa U.O.
Galante V.C.
spellingShingle Focaccia R.
Siciliano R.F.
Santos E.D.B.
Boccardo E.
Conceição O.J.G.
Barbosa U.O.
Galante V.C.
Hepatitis C: a critical analysis of therapeutic response predictors
Brazilian Journal of Infectious Diseases
ALT normalization
hepatitis C
viral load reduction
author_facet Focaccia R.
Siciliano R.F.
Santos E.D.B.
Boccardo E.
Conceição O.J.G.
Barbosa U.O.
Galante V.C.
author_sort Focaccia R.
title Hepatitis C: a critical analysis of therapeutic response predictors
title_short Hepatitis C: a critical analysis of therapeutic response predictors
title_full Hepatitis C: a critical analysis of therapeutic response predictors
title_fullStr Hepatitis C: a critical analysis of therapeutic response predictors
title_full_unstemmed Hepatitis C: a critical analysis of therapeutic response predictors
title_sort hepatitis c: a critical analysis of therapeutic response predictors
publisher Elsevier
series Brazilian Journal of Infectious Diseases
issn 1413-8670
1678-4391
publishDate 2002-01-01
description Treatment of chronic hepatitis C is still unspecific. However, there is great expectancy concerning the new pegylated interferons. As there has been much controversy about the best parameters to determine whether treatment is effective, we analyzed several criteria currently used for evaluation, including serum alanine aminotransferase (ALT) normalization, viral load reduction and improvement of hepatic histology.
topic ALT normalization
hepatitis C
viral load reduction
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000200003
work_keys_str_mv AT focacciar hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT sicilianorf hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT santosedb hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT boccardoe hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT conceicaoojg hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT barbosauo hepatitiscacriticalanalysisoftherapeuticresponsepredictors
AT galantevc hepatitiscacriticalanalysisoftherapeuticresponsepredictors
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