Elimination of HIV-1-Infected Primary T Cell Reservoirs in an In Vitro Model of Latency.

Establishment of long-lived cellular reservoirs of HIV-1 represents a major therapeutic challenge to virus eradication. In this study, we utilized a human primary cell model of HIV-1 latency to evaluate the requirements for efficient virus reactivation from, and the selective elimination of, latentl...

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Bibliographic Details
Main Authors: Stephen A Rawlings, Francis Alonzo, Lina Kozhaya, Victor J Torres, Derya Unutmaz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4437782?pdf=render

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