Insight of the cytotoxicity of the aggregates of peptides or aberrant proteins: a meta-analysis.
Aberrant proteins or peptide aggregates form soluble oligomers or nanofibrils that can cause a wide range of amyloidosis diseases, including Alzheimer's disease (AD). The mechanisms of their cytotoxicity, however, remain controversial and poorly understood, greatly hindering the development of...
Main Authors: | Rong Zhou, Bing Xu |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4000214?pdf=render |
Similar Items
-
Molecular Lysine Tweezers Counteract Aberrant Protein Aggregation
by: Inesa Hadrovic, et al.
Published: (2019-10-01) -
Insights Into Peptide Inhibition of Alpha-Synuclein Aggregation
by: James H. Torpey, et al.
Published: (2020-10-01) -
Designed Cell-Penetrating Peptide Inhibitors of Amyloid-beta Aggregation and Cytotoxicity
by: Anja Henning-Knechtel, et al.
Published: (2020-02-01) -
Structure-Based Peptide Design to Modulate Amyloid Beta Aggregation and Reduce Cytotoxicity.
by: Jitendra Kumar, et al.
Published: (2015-01-01) -
Nanoparticles in relation to peptide and protein aggregation
by: Zaman M, et al.
Published: (2014-02-01)