Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer

Calcium is a critical regulator of cell death pathways. One of the most proximal events leading to cell death is activation of plasma membrane and endoplasmic reticulum-resident calcium channels. A large body of evidence indicates that defects in this pathway contribute to cancer development. Althou...

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Bibliographic Details
Main Authors: Jessica J. Chen, Darren Boehning
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Oncology
Subjects:
Fas
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00138/full