Role of CYP27A in cholesterol and bile acid metabolism

Role of CYP27A in cholesterol and bile acid metabolism

The CYP27A gene encodes a mitochondrial cytochrome P450 enzyme, sterol 27-hydroxylase, that is expressed in many different tissues and plays an important role in cholesterol and bile acid metabolism. In humans, CYP27A deficiency leads to cerebrotendinous xanthomatosis. To gain insight into the roles...

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Bibliographic Details
Main Authors: Sandrine Dubrac, Steven R. Lear, Meena Ananthanarayanan, Natarajan Balasubramaniyan, Jaya Bollineni, Sarah Shefer, Hideyuki Hyogo, David E. Cohen, Patricia J. Blanche, Ronald M. Krauss, Ashok K. Batta, Gerald Salen, Frederick J. Suchy, Nobuyo Maeda, Sandra K. Erickson
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Lipid Research
Subjects:
liver
lipoproteins
lipid synthesis
fatty acids
bile alcohols
cyp7A
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340839

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http://www.sciencedirect.com/science/article/pii/S0022227520340839

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