DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies
Dry films of platinum chemotherapeutic drugs covalently bound to plasmid DNA (Pt-DNA) represent a useful experimental model to investigate direct effects of radiation on DNA in close proximity to platinum chemotherapeutic agents, a situation of considerable relevance to understand the mechanisms und...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Bioinorganic Chemistry and Applications |
Online Access: | http://dx.doi.org/10.1155/2012/923914 |