Determination of Inherent Dissolution Performance of Drug Substances

Determination of Inherent Dissolution Performance of Drug Substances

The dissolution behavior of novel active pharmaceutical ingredients (API) is a crucial parameter in drug formulation since it frequently affects the drug release. Generally, a distinction is made between surface-reaction- and diffusion-controlled drug release. Therefore, dissolution studies such as...

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Bibliographic Details
Main Authors: Dominik Sleziona, Amelie Mattusch, Gerhard Schaldach, David R. Ely, Gabriele Sadowski, Markus Thommes
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
drug release
flow channel
intrinsic dissolution
surface reaction
two-film theory
Online Access:https://www.mdpi.com/1999-4923/13/2/146

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