Levodopa-Reduced Mucuna pruriens Seed Extract Shows Neuroprotective Effects against Parkinson’s Disease in Murine Microglia and Human Neuroblastoma Cells, Caenorhabditis elegans, and Drosophila melanogaster

Levodopa-Reduced Mucuna pruriens Seed Extract Shows Neuroprotective Effects against Parkinson’s Disease in Murine Microglia and Human Neuroblastoma Cells, Caenorhabditis elegans, and Drosophila melanogaster

Mucuna pruriens (Mucuna) has been prescribed in Ayurveda for various brain ailments including ‘kampavata’ (tremors) or Parkinson’s disease (PD). While Mucuna is a well-known natural source of levodopa (L-dopa), published studies suggest that other bioactive compounds ma...

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Bibliographic Details
Main Authors: Shelby L. Johnson, Hyun Y. Park, Nicholas A. DaSilva, Dhiraj A. Vattem, Hang Ma, Navindra P. Seeram
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Nutrients
Subjects:
Mucuna pruriens
levodopa
Parkinson’s disease
neuroprotection
Caenorhabditis elegans
Drosophila melanogaster
Online Access:http://www.mdpi.com/2072-6643/10/9/1139

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