TNF-α/TNF-R System May Represent a Crucial Mediator of Proliferative Synovitis in Hemophilia A

TNF-α/TNF-R System May Represent a Crucial Mediator of Proliferative Synovitis in Hemophilia A

Hemophilic arthropathy (HA) typically begins with proliferative synovitis that shares some similarities with inflammatory arthritides, in which the proinflammatory cytokine tumor necrosis factor (TNF)-α has a crucial pathogenetic role. Inappropriate release of TNF-α was shown to co...

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Bibliographic Details
Main Authors: Mirko Manetti, Silvia Linari, Eloisa Romano, Irene Rosa, Christian Carulli, Massimo Innocenti, Marco Matucci-Cerinic, Lidia Ibba-Manneschi, Giancarlo Castaman, Daniela Melchiorre
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Journal of Clinical Medicine
Subjects:
hemophilic arthropathy
TNF-α
TNF receptors
fibroblast-like synoviocytes
proliferative synovitis
Online Access:https://www.mdpi.com/2077-0383/8/7/939

Internet

https://www.mdpi.com/2077-0383/8/7/939

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