| Summary: | Pathomorphological study of the neonatal period piglets of ontogenesis from the pig breeding complex obtained from sows that were given feed contaminated with mycotoxins during pregnancy and after parturition was carried out. Pathological changes in the internal organs of piglets, characterized by various dystrophic and inflammatory processes resulting from the influence of mycotoxins, were established. Edema and congestion in the lungs of piglets is noted as a sign of circulation failure in the body. Signs of interstitial pneumonia are detected with areas of chronic alveolar emphysema and atelectasis. Signs of granular dystrophy were noted in the heart in cardiomyocytes. Interstitial connective tissue has signs of edema; the swelling of blood vessel walls is noted. The morphofunctional state of the thyroid gland in piglets, taking into account changes in the organ structure, is characterized as a macro-microfollicular proliferating colloid goiter. The border smoothness between white and red pulp, hyperemia of blood vessels and the small number of lymphatic nodules with a size decrease are noted in the spleen. The demarcation clarity of white pulp into separate structural zones is not diagnosed in lymphatic nodules. Signs of catarrhal enteritis and chronic catarrhal colitis with a tendency to its transition to atrophic catarrh are detected in the small and large intestines of the gastrointestinal tract. Hepatocytes have mild signs of granular dystrophy in the lobules of the piglets’ liver. Protein hepatosis signs interspersed with areas of necrobiosis are identified in separate lobules of the organ against the background of general atrophy of hepatocytes. Granular dystrophy signs with the phenomena of its desquamation in certain areas are revealed in the convoluted tubules of kidney nephrons in epithelial cells. Part of epithelial cells of the nephron tubule is subject to necrobiotic processes. Thickening of the basic capillary membrane with glomerulitis is noted in the glomerulus of the renal corpuscle. Edema and mild lymphocyte-macrophage infiltration with the phenomena of the mucoid swelling of blood vessel walls is observed in the interstitial organ tissue.
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