G6PD: A hub for metabolic reprogramming and redox signaling in cancer

Metabolic hubs play a major role in the initiation and development of cancer. Oncogenic signaling pathways drive metabolic reprogramming and alter redox homeostasis. G6PD has potential oncogenic activity and it plays a pivotal role in cell proliferation, survival and stress responses. Aberrant activ...

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Bibliographic Details
Main Authors: Hung-Chi Yang, Arnold Stern, Daniel Tsun-Yee Chiu
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417020301347