Current insights in to the pathophysiology of Irritable Bowel Syndrome

<p>Abstract</p> <p>Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with altered bowel habits.</p> <p>IBS includes...

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Main Authors: Karantanos Theodoros, Markoutsaki Theofano, Gazouli Maria, Anagnou Nicholas P, Karamanolis Dimitrios G
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Gut Pathogens
Online Access:http://www.gutpathogens.com/content/2/1/3
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spelling doaj-f63f8dd130284bb0b2379497ce4603942020-11-24T21:27:40ZengBMCGut Pathogens1757-47492010-05-0121310.1186/1757-4749-2-3Current insights in to the pathophysiology of Irritable Bowel SyndromeKarantanos TheodorosMarkoutsaki TheofanoGazouli MariaAnagnou Nicholas PKaramanolis Dimitrios G<p>Abstract</p> <p>Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with altered bowel habits.</p> <p>IBS includes a wide range of symptoms while its pathophysiology is very complicated. Recent studies indicate that the most important mechanisms include visceral sensitivity, abnormal gut motility and autonomous nervous system dysfunction. The interactions between these three mechanisms make bowel's function susceptible to many exogenous and endogenous factors like gastrointestinal flora, feeding and psychosocial factors. Recent data indicate that according to the above mechanisms, the influence of genetic factors and polymorphisms of human DNA in the development of IBS is equally important.</p> http://www.gutpathogens.com/content/2/1/3
collection DOAJ
language English
format Article
sources DOAJ
author Karantanos Theodoros
Markoutsaki Theofano
Gazouli Maria
Anagnou Nicholas P
Karamanolis Dimitrios G
spellingShingle Karantanos Theodoros
Markoutsaki Theofano
Gazouli Maria
Anagnou Nicholas P
Karamanolis Dimitrios G
Current insights in to the pathophysiology of Irritable Bowel Syndrome
Gut Pathogens
author_facet Karantanos Theodoros
Markoutsaki Theofano
Gazouli Maria
Anagnou Nicholas P
Karamanolis Dimitrios G
author_sort Karantanos Theodoros
title Current insights in to the pathophysiology of Irritable Bowel Syndrome
title_short Current insights in to the pathophysiology of Irritable Bowel Syndrome
title_full Current insights in to the pathophysiology of Irritable Bowel Syndrome
title_fullStr Current insights in to the pathophysiology of Irritable Bowel Syndrome
title_full_unstemmed Current insights in to the pathophysiology of Irritable Bowel Syndrome
title_sort current insights in to the pathophysiology of irritable bowel syndrome
publisher BMC
series Gut Pathogens
issn 1757-4749
publishDate 2010-05-01
description <p>Abstract</p> <p>Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with altered bowel habits.</p> <p>IBS includes a wide range of symptoms while its pathophysiology is very complicated. Recent studies indicate that the most important mechanisms include visceral sensitivity, abnormal gut motility and autonomous nervous system dysfunction. The interactions between these three mechanisms make bowel's function susceptible to many exogenous and endogenous factors like gastrointestinal flora, feeding and psychosocial factors. Recent data indicate that according to the above mechanisms, the influence of genetic factors and polymorphisms of human DNA in the development of IBS is equally important.</p>
url http://www.gutpathogens.com/content/2/1/3
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