Current insights in to the pathophysiology of Irritable Bowel Syndrome
<p>Abstract</p> <p>Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with altered bowel habits.</p> <p>IBS includes...
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doaj-f63f8dd130284bb0b2379497ce4603942020-11-24T21:27:40ZengBMCGut Pathogens1757-47492010-05-0121310.1186/1757-4749-2-3Current insights in to the pathophysiology of Irritable Bowel SyndromeKarantanos TheodorosMarkoutsaki TheofanoGazouli MariaAnagnou Nicholas PKaramanolis Dimitrios G<p>Abstract</p> <p>Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with altered bowel habits.</p> <p>IBS includes a wide range of symptoms while its pathophysiology is very complicated. Recent studies indicate that the most important mechanisms include visceral sensitivity, abnormal gut motility and autonomous nervous system dysfunction. The interactions between these three mechanisms make bowel's function susceptible to many exogenous and endogenous factors like gastrointestinal flora, feeding and psychosocial factors. Recent data indicate that according to the above mechanisms, the influence of genetic factors and polymorphisms of human DNA in the development of IBS is equally important.</p> http://www.gutpathogens.com/content/2/1/3 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Karantanos Theodoros Markoutsaki Theofano Gazouli Maria Anagnou Nicholas P Karamanolis Dimitrios G |
spellingShingle |
Karantanos Theodoros Markoutsaki Theofano Gazouli Maria Anagnou Nicholas P Karamanolis Dimitrios G Current insights in to the pathophysiology of Irritable Bowel Syndrome Gut Pathogens |
author_facet |
Karantanos Theodoros Markoutsaki Theofano Gazouli Maria Anagnou Nicholas P Karamanolis Dimitrios G |
author_sort |
Karantanos Theodoros |
title |
Current insights in to the pathophysiology of Irritable Bowel Syndrome |
title_short |
Current insights in to the pathophysiology of Irritable Bowel Syndrome |
title_full |
Current insights in to the pathophysiology of Irritable Bowel Syndrome |
title_fullStr |
Current insights in to the pathophysiology of Irritable Bowel Syndrome |
title_full_unstemmed |
Current insights in to the pathophysiology of Irritable Bowel Syndrome |
title_sort |
current insights in to the pathophysiology of irritable bowel syndrome |
publisher |
BMC |
series |
Gut Pathogens |
issn |
1757-4749 |
publishDate |
2010-05-01 |
description |
<p>Abstract</p> <p>Irritable Bowel Syndrome (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect, in which abdominal pain is relieved with defecation and is associated with altered bowel habits.</p> <p>IBS includes a wide range of symptoms while its pathophysiology is very complicated. Recent studies indicate that the most important mechanisms include visceral sensitivity, abnormal gut motility and autonomous nervous system dysfunction. The interactions between these three mechanisms make bowel's function susceptible to many exogenous and endogenous factors like gastrointestinal flora, feeding and psychosocial factors. Recent data indicate that according to the above mechanisms, the influence of genetic factors and polymorphisms of human DNA in the development of IBS is equally important.</p> |
url |
http://www.gutpathogens.com/content/2/1/3 |
work_keys_str_mv |
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