Stem Cell Theory of Cancer: Origin of Tumor Heterogeneity and Plasticity

In many respects, heterogeneity is one of the most striking revelations and common manifestations of a stem cell origin of cancer. We observe heterogeneity in myriad mixed tumors including testicular, lung, and breast cancers. We recognize heterogeneity in diverse tumor subtypes in prostate and kidn...

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Bibliographic Details
Main Authors: Shi-Ming Tu, Miao Zhang, Christopher G. Wood, Louis L. Pisters
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/16/4006