Exosomal lipids impact notch signaling and induce death of human pancreatic tumoral SOJ-6 cells.

Exosomal lipids impact notch signaling and induce death of human pancreatic tumoral SOJ-6 cells.

Exosomes are of increasing interest as alternative mode of cell-to-cell communication. We previously reported that exosomes secreted by human SOJ-6 pancreatic tumor cells induce (glyco)protein ligand-independent cell death and inhibit Notch-1 pathway, this latter being particularly active during car...

Full description

Bibliographic Details
Main Authors: Sadia Beloribi, Elodie Ristorcelli, Gilles Breuzard, Françoise Silvy, Justine Bertrand-Michel, Evelyne Beraud, Alain Verine, Dominique Lombardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3477155?pdf=render

Similar Items

Similar Items