Apoptotic Pathways in Pemphigus

Pemphigus is a group of human autoimmune blistering diseases of the skin in which autoantibodies to desmosome cadherins induce loss of cell-cell adhesion (acantholysis). In addition to steric hindrance and activation of intracellular signaling, apoptosis has been suggested to contribute to the mecha...

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Bibliographic Details
Main Authors: Meryem Bektas, Puneet Jolly, David S. Rubenstein
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/456841