Apoptotic Pathways in Pemphigus
Pemphigus is a group of human autoimmune blistering diseases of the skin in which autoantibodies to desmosome cadherins induce loss of cell-cell adhesion (acantholysis). In addition to steric hindrance and activation of intracellular signaling, apoptosis has been suggested to contribute to the mecha...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2010-01-01
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Series: | Dermatology Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2010/456841 |