Airway Mucus and Asthma: The Role of MUC5AC and MUC5B
Asthma is characterized by mucus abnormalities. Airway epithelial hyperplasia and metaplasia result in changes in stored and secreted mucin and the production of a pathologic mucus gel. Mucus transport is impaired, culminating in mucus plugging and airway obstruction—a major cause of morbidity in as...
Main Authors: | Luke R. Bonser, David J. Erle |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-11-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/6/12/112 |
Similar Items
-
Integrin β1 subunit regulates cellular and secreted MUC5AC and MUC5B production in NCI–H292 human lung epithelial cells
by: Jun Iwashita, et al.
Published: (2021-12-01) -
Overexpression of Substance P in pig airways increases MUC5AC through an NF‐kβ pathway
by: Mariana Sponchiado, et al.
Published: (2021-02-01) -
Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas
by: Onur Oral, et al.
Published: (2020-01-01) -
Carbocisteine inhibits the expression of Muc5b in COPD mouse model
by: Song Y, et al.
Published: (2019-09-01) -
Muc5ac mucin expression during rat skin development
by: V. Ferretti, et al.
Published: (2015-02-01)