Mitotic Acetylation of Microtubules Promotes Centrosomal <i>PLK1</i> Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis

Mitotic Acetylation of Microtubules Promotes Centrosomal <i>PLK1</i> Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis

Tubulin post-translational modifications regulate microtubule properties and functions. Mitotic spindle microtubules are highly modified. While tubulin detyrosination promotes proper mitotic progression by recruiting specific microtubule-associated proteins motors, tubulin acetylation that occurs on...

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Bibliographic Details
Main Authors: Sylvia Fenosoa Rasamizafy, Claude Delsert, Gabriel Rabeharivelo, Julien Cau, Nathalie Morin, Juliette van Dijk
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
microtubules
acetylation
acetyltransferase <i>ATAT1</i>
mitosis
spindle
centrosome
Online Access:https://www.mdpi.com/2073-4409/10/8/1859

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