Differential Modulation of Mouse Heart Gene Expression by Infection With Two Trypanosoma cruzi Strains: A Transcriptome Analysis

Differential Modulation of Mouse Heart Gene Expression by Infection With Two Trypanosoma cruzi Strains: A Transcriptome Analysis

The protozoan Trypanosoma cruzi (T. cruzi) is a well-adapted parasite to mammalian hosts and the pathogen of Chagas disease in humans. As both host and T. cruzi are highly genetically diverse, many variables come into play during infection, making disease outcomes difficult to predict. One important...

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Bibliographic Details
Main Authors: Tiago Bruno Rezende de Castro, Maria Cecilia Campos Canesso, Mariana Boroni, Daniela Ferreira Chame, Daniela de Laet Souza, Nayara Evelin de Toledo, Eric Birelli Tahara, Sergio Danilo Pena, Carlos Renato Machado, Egler Chiari, Andrea Macedo, Gloria Regina Franco
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
Trypanosoma cruzi
host-parasite interaction
heart transcriptome
immune system
differential gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.01031/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.01031/full

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