Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress.

Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. However, the mechanisms via which this occurs remain elusive, precluding the identification of potential therapy. Using an integrative approach at t...

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Bibliographic Details
Main Authors: Dino A Giussani, Emily J Camm, Youguo Niu, Hans G Richter, Carlos E Blanco, Rachel Gottschalk, E Zachary Blake, Katy A Horder, Avnesh S Thakor, Jeremy A Hansell, Andrew D Kane, F B Peter Wooding, Christine M Cross, Emilio A Herrera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3278440?pdf=render

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