Diabetes mellitus associated with pancreatic somatostatin tumor: A case report

The finding of diabetes in association with a pancreatic neuroendocrine tumor (PNET) in patients is uncommon. Here, we describe a 74-year-old diabetes patient with a tumor in the pancreatic head. Calcification in the central part of the tumor and significant expansion of the pancreatic duct were als...

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Main Authors:	Bing Han, MD, Hualin Zhai, MD, Jiao Yu, MD, Fangzhen Xia, MD, Yingli Lu, MD
Format:	Article
Language:	English
Published:	Elsevier 2016-12-01
Series:	Journal of Clinical and Translational Endocrinology Case Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214624516300107

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spelling	doaj-f60b056a8cc540c9aaa61b8644a223b02020-11-24T23:26:40ZengElsevierJournal of Clinical and Translational Endocrinology Case Reports2214-62452016-12-0122022Diabetes mellitus associated with pancreatic somatostatin tumor: A case reportBing Han, MD0Hualin Zhai, MD1Jiao Yu, MD2Fangzhen Xia, MD3Yingli Lu, MD4Department of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, ChinaDepartment of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, ChinaDepartment of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, ChinaDepartment of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, ChinaCorresponding author. Department of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Tel.: +86 21 23271699; Department of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, ChinaThe finding of diabetes in association with a pancreatic neuroendocrine tumor (PNET) in patients is uncommon. Here, we describe a 74-year-old diabetes patient with a tumor in the pancreatic head. Calcification in the central part of the tumor and significant expansion of the pancreatic duct were also detected. In addition, the patient had a gallstone, which was surgically resected. During surgery, the pancreatic tumor was biopsied. DNA was extracted from peripheral leukocytes, and MEN1 was excluded by direct sequencing of the MEN1 gene. After biochemical and immunohistochemical analyses, a pancreatic somatostatin tumor was diagnosed. Keywords: Specific type, Diabetes, Pancreatic somatostatin tumorhttp://www.sciencedirect.com/science/article/pii/S2214624516300107
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Bing Han, MD Hualin Zhai, MD Jiao Yu, MD Fangzhen Xia, MD Yingli Lu, MD
spellingShingle	Bing Han, MD Hualin Zhai, MD Jiao Yu, MD Fangzhen Xia, MD Yingli Lu, MD Diabetes mellitus associated with pancreatic somatostatin tumor: A case report Journal of Clinical and Translational Endocrinology Case Reports
author_facet	Bing Han, MD Hualin Zhai, MD Jiao Yu, MD Fangzhen Xia, MD Yingli Lu, MD
author_sort	Bing Han, MD
title	Diabetes mellitus associated with pancreatic somatostatin tumor: A case report
title_short	Diabetes mellitus associated with pancreatic somatostatin tumor: A case report
title_full	Diabetes mellitus associated with pancreatic somatostatin tumor: A case report
title_fullStr	Diabetes mellitus associated with pancreatic somatostatin tumor: A case report
title_full_unstemmed	Diabetes mellitus associated with pancreatic somatostatin tumor: A case report
title_sort	diabetes mellitus associated with pancreatic somatostatin tumor: a case report
publisher	Elsevier
series	Journal of Clinical and Translational Endocrinology Case Reports
issn	2214-6245
publishDate	2016-12-01
description	The finding of diabetes in association with a pancreatic neuroendocrine tumor (PNET) in patients is uncommon. Here, we describe a 74-year-old diabetes patient with a tumor in the pancreatic head. Calcification in the central part of the tumor and significant expansion of the pancreatic duct were also detected. In addition, the patient had a gallstone, which was surgically resected. During surgery, the pancreatic tumor was biopsied. DNA was extracted from peripheral leukocytes, and MEN1 was excluded by direct sequencing of the MEN1 gene. After biochemical and immunohistochemical analyses, a pancreatic somatostatin tumor was diagnosed. Keywords: Specific type, Diabetes, Pancreatic somatostatin tumor
url	http://www.sciencedirect.com/science/article/pii/S2214624516300107
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Diabetes mellitus associated with pancreatic somatostatin tumor: A case report

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