A differential role for macropinocytosis in mediating entry of the two forms of vaccinia virus into dendritic cells.

A differential role for macropinocytosis in mediating entry of the two forms of vaccinia virus into dendritic cells.

Vaccinia virus (VACV) is being developed as a recombinant viral vaccine vector for several key pathogens. Dendritic cells (DCs) are specialised antigen presenting cells that are crucial for the initiation of primary immune responses; however, the mechanisms of uptake of VACV by these cells are uncle...

Full description

Bibliographic Details
Main Authors: Kerrie J Sandgren, John Wilkinson, Monica Miranda-Saksena, Gerald M McInerney, Karen Byth-Wilson, Phillip J Robinson, Anthony L Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2858709?pdf=render

Similar Items

Similar Items