A computational framework for identifying the transcription factors involved in enhancer-promoter loop formation

The pairwise interaction between transcription factors (TFs) plays an important role in enhancer-promoter loop formation. Although thousands of TFs in the human genome have been found, only a few TF pairs have been demonstrated to be related to loop formation. It is still a challenge to determine wh...

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Bibliographic Details
Main Authors: Li Liu, Li-Rong Zhang, Fu-Ying Dao, Yan-Chao Yang, Hao Lin
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312030367X

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